PepEvolution
Research Blog

Peptide Research Blog

Evidence-based articles on peptide science — from beginner introductions to clinician-grade regulatory analysis. Every article is cited. No hype, no dosing prescriptions.

Beginner Enthusiast Fitness Weight Loss Health Specialist Clinician
ArticleFitness

AOD-9604: The HGH Fragment Designed for Fat Metabolism

AOD-9604 is a synthetic fragment of human growth hormone engineered to isolate its fat-burning properties without the side effects of full HGH. Here's what the research actually shows — and where the evidence runs thin.

#aod-9604#hgh fragment#lipolysis
ArticleWeight Loss

Tirzepatide vs Semaglutide: What the Clinical Trials Actually Show

The first head-to-head randomized trial comparing tirzepatide and semaglutide for weight loss is in. Here's what SURMOUNT-5 found — and what the full body of evidence tells us about how these two peptide therapies compare.

#tirzepatide#semaglutide#weight-loss
ArticleBeginner

Are Peptides Safe? What the Research Actually Shows

Safety is the first question anyone should ask about peptides. Here's an honest, evidence-based look at what we know, what we don't know, and how to think about risk when evaluating peptide use.

#safety#beginner#research
ArticleClinician

Compounded Peptides and the 503A/503B Landscape in 2026

The regulatory framework governing compounded peptides is undergoing its most significant changes in a decade. Here's the authoritative breakdown of 503A vs. 503B, the PCAC July 2026 review, and what it means for practitioners and patients.

#regulation#503a#503b
ArticleHealth

GLP-1 Receptor Agonists: Mechanisms Beyond Weight Loss

GLP-1 receptor agonists like semaglutide and tirzepatide are famous for weight loss, but the science reveals a far richer picture — cardiovascular protection, neurological effects, and metabolic benefits that go well beyond the scale.

#glp-1#semaglutide#tirzepatide
ArticleEnthusiast

GH Secretagogues 101: Ipamorelin vs CJC-1295

Growth hormone secretagogues like Ipamorelin and CJC-1295 work by stimulating your body's own GH release rather than replacing it externally. Here's how they work, how they differ, and what the research shows.

#ipamorelin#cjc-1295#growth hormone
ArticleEnthusiast

Peptides for Recovery: BPC-157 and TB-500 Explained

BPC-157 and TB-500 are the two most-discussed recovery peptides in athletic and fitness circles. Here's what the research actually says about how they work, why they're often stacked, and what the evidence looks like.

#bpc-157#tb-500#recovery
ArticleBeginner

How to Read a Peptide COA: Spotting a Legit Vendor

A Certificate of Analysis (COA) is your best tool for evaluating peptide vendor quality. Learn what a real COA contains, what red flags to look for, and how to verify a vendor isn't faking their testing.

#sourcing#coa#vendor quality
ArticleBeginner

What Is BPC-157? A Beginner's Guide

BPC-157 is one of the most-discussed research peptides in wellness communities — but what is it actually? This plain-language guide explains the science, what researchers have studied, and what you should know.

#bpc-157#healing#beginner

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