What is Semax's PepScore grade?

Semax holds a PepScore of 67/100 (band B, Viable), graded across Evidence, Sourcing & COA, Safety, and Practicality. A substantial (if largely non-Western) evidence base and easy intranasal dosing; sourcing transparency is the main drag. Viable for the informed.

Where can I buy Semax that is third-party tested?

PepEvolution's best-sourced vendor for Semax is Hydro Research Peptides, ranked by Source Match (vendor grade times batch-matched independent COA freshness). Vetted options with a COA on file: Hydro Research Peptides (vendor grade 80, band A); Amino Club (vendor grade 83, band A); BioLongevity Labs (vendor grade 83, band A, an affiliate partner (disclosed)). Affiliate links are disclosed and never influence grades or ranking.

Home›Rankings›Semax

CognitivePreliminary grade

Semax

A heavily-researched (largely Russian) nootropic/neuroprotective peptide, easy intranasal dosing.

Verdict, B · Viable

A substantial (if largely non-Western) evidence base and easy intranasal dosing; sourcing transparency is the main drag. Viable for the informed.

PepScore / 100

BViable

How we compute this →

Overview

Semax is a synthetic ACTH-derived heptapeptide developed in Russia for stroke and cognitive disorders, and one of the most-studied cognitive peptides, a potent BDNF upregulator. Most clinical data originate outside Western registries; sourcing is moderate.

PepScore Breakdown, the four axes

Evidence

35% weight

49/100

How strong is the published human science?

Human data depth20/40

Regulatory & registry status10/30

Reproducibility & consistency12/20

Mechanism characterized in humans7/10

Sourcing & COA

30% weightOur moat

72/100

Can a buyer obtain an independently-verified, high-purity version?, our proprietary layer.

Independent + portal-verifiable testing25/35

Method transparency (HPLC + MS + endotoxin/sterility, methods stated)18/25

Lot-matched + recent18/25

Independent corroboration11/15

Safety & Risk

25% weight

80/100

What is the real-world harm potential?

Documented AEs / toxicity34/40

Contraindication breadth20/25

Regulatory warnings13/20

Therapeutic index / margin13/15

Practicality

10% weight

80/100

How easy is it to actually run a verified version?

Verified-source availability28/35

Cost / value per cycle19/25

Reconstitution & administration22/25

Storage & stability11/15

Sources & Citations

Every claim cites a primary source. Citations are machine-audited against NCBI, see methodology.

→Semax, neuroprotection & BDNF (PubMed)

Best-Sourced Vendor

Hydro Research Peptides

Vendor 80 · A

Strong vendor grade (A) and the best verified supply right now for Semax, batch-matched independent COA freshness 78%.

Visit Hydro Research Peptides ↗

Ranked by Source Match = Vendor Grade × batch-COA freshness. Affiliate status is never an input to any grade, and a paying vendor never outranks a non-paying one on a tie.How this works →

Want a clinical path?

Talk to a licensed provider about Semax and whether it's appropriate for your situation.

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Telehealth. Not medical advice, for educational purposes.

PepScore67/100 · B

Last gradedJune 28, 2026

Next re-grade triggerWestern registered trials or broader COA coverage would lift the grade.

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Educational only, not medical advice. PepScore is an educational research grade, not a prescription or dosing recommendation. Some vendor links are affiliate links, this never affects grades. Consult a licensed healthcare provider before using any compound.